Edward Muse, son of JOHN MUSE, Jr., and his wife, ANN, lived in Westmoreland County. He had leased lands in 1734 in Westmoreland County from ROBERT SANDFORD [ Jr.] and MARY, his wife, who was a sister of Edward Muse. Edward had married Ann, daughter of Richard Sanford, Sr., and his wife, Susannah [surname unknown.] He had a grandson, Sanford Muse, who was mentioned in his will. Edward died in 1781, leaving a will, naming his children and widow.

There were other Muse-Sanford marriages, too; Thomas Muse, Jr. [b. 1712- d. 1734] married Sarah Sanford. John Muse [b. 1700- d. 1777] married Mary Sanford.

Children of Robert Sanford-“2” and Mary Muse

1. Robert Sanford-3, died by 1738. His will is found on page 43 of Will Book VIII, Westmoreland County, Virginia, dated March 23, 1737, and probated August 29, 1738, and mentions sons Augustine and Joshua, “my mother, MARY [MUSE] SANFORD, now living,” son, Robert-4, and “my six daughters,” [which included] Elizabeth-4 and Mary-4. Executors, Edward Muse and PRESLEY NEALE [who was his brother-in-law, married to his sister, MARGARET SANFORD.]

2. John Sanford-3. There were several men with this identical name. The John Sanford, who deeded gifts in 1750, mentioned that he had two brothers, Robert and James. Each of his brothers had a son named Robert, called “Robert, Sr.”, and “Robert, Jr.,” and he left gifts to them. He also mentioned his own children, son, Willouhby Sanford, and daughter, Jemima, who was married to Thomas Spence, Jr. It is possible that this John Sanford was the brother of ROBERT-1, and the uncle of Robert-2, who died shortly after ROBERT-1 SANFORD, his father [?]. It is even remotely possible that our ROBERT SANFORD-1 is the man accused of swearing in 1673. It is also possible that there is an intervening generation, as mentioned above. So there are still several unanswered questions. Ann Butler, in a will dated 1763 [Will Book XV, Westmoreland Co., VA, pg. 67] mentions “granddaughter Sarah, daughter of Mary Sanford” and “Willoughby Sanford, son-in-law.”

3. Joseph Sanford-3

4. Jemima Sanford-3, married someone named Minor. Note that the John Sanford who gave the gifts [in #2] had a daughter named Jemima also.

5. Ann Sanford-3, unmarried at time of father’s will.

6. Elizabeth Sanford-3, unmarried at time of father’s will.

7. MARGARET SANFORD-3, married PRESLEY NEALE.

8. Unnamed daughter? who married Richard Morton. Will book VIII Westmoreland County, page 38, contains will of Richard Morton, dated November 18, 1732, which mentions wife, Massey, and “my children.” The executor was “father-in-law,” Robert Sanford, Sr.

MARGARET SANFORD NEALE’s mother was MARY MUSE. HENRY WISHEART bought 268 acres of land from Edward Muse in 1759 [Fairfax Deeds D:618.] This gives us a bit of information about HENRY, including that he was at least adult [age 21 by 1759] and that he was in the colony by that time or before. Edward Muse had bought these lands in 1751. [Fairfax Deeds C:278.] He was probably the Edward Muse who was an uncle of MARGARET’S.